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01-Apr-2009
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Arch Hellen Med, 26(1), January-February 2009, 59-62 BRIEF REVIEW Hematological laboratory contribution to the survival of multiply injured patients S. CHANIOTAKI, E. PAPAKONSTANTINOU, A. SKOURBOUTI, P. GEORGOUTSOU, A. LAVDA, K. SAFIOLEAS, C. MANTI |
Measurement of the full blood count-hematocrit, hemoglobin, platelets and coagulation-fibrinolysis markers carried out in the Hematological Laboratory are critical for the treatment of the multiply injured patient. Coagulation disorders associated with major blood loss are (a) consumption of coagulation factors and platelets, (b) reduction of coagulation factors and platelets due to hemodilution, (c) functional abnormality of platelets, (d) dysfunction in coagulation pathways, (e) increased fibrinolytic activity, (f ) hypocalcemia, and (g) disseminated intravascular coagulation (DIC). Hypothermia and metabolic acidosis following injury may burden the patient’s condition, interfering in the coagulation cascade. Consumption of coagulation factors and platelets cause severe bleeding. The survival of the multiply injured patient depends on many parameters. The hematological laboratory contributes to the early diagnosis of anemia and coagulation disorders playing a critical role in the treatment and survival of multiply injured patients.
Key words: Bleeding, Coagulation disorders, Multiply injured patient.
