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16-Sep-2021
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Arch Hellen Med, 38(5), September-October 2021, 657-659 CASE REPORT Is high Ki-67 proliferation index in grade II oligodendroglioma an important marker for adjuvant therapy? Y.B. Cihan,1 K. Eser2 |
Treatment decisions for oligodendrogliomas are usually made according to clinical variables. With the development of determination of genetic and epigenetic pathways, new approaches to treatment have been introduced. In this case report, the treatment approach was evaluated in a patient with high grade II oligodendroglioma whose Ki-67 proliferation index was investigated. There is a need for studies investigating the contribution of the Ki-67 proliferation index to treatment decisions, as an addition to 1p/19q combined deletion, and IDH1, IDH2 mutations in grade II oligodendrogliomas.
Key words: Grade II oligodendroglioma, Ki-67 proliferation index, Prognosis, Treatment.
