Last update:
   24-Jan-2024
 

Arch Hellen Med, 41(1), January-February 2024, 134-137

CASE REPORT

Food protein-induced enterocolitis syndrome (FPIES) not responding to amino acid formula

A. Kourti,1 C. Kosmeri,1 C. Chliva,2 K. Douros,1 V. Papaevangelou,1 S. Fessatou1
1Third Department of Pediatrics, "Attikon" General University Hospital, National and Kapodistrian University of Athens, Athens
2"D. Kalogeromitros" Allergy Unit, Second Department of Dermatology and Venereology, "Attikon" General University Hospital,
National and Kapodistrian University of Athens, Athens, Greece

Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE cell mediated food allergy triggered by the ingestion of specific food proteins that may manifest in an acute or chronic form. We report a case of an infant with severe chronic FPIES presenting in the neonatal period that failed to respond to amino acid-based formulas. The patient remained on total parenteral nutrition for 4 weeks and after that he could tolerate amino acid formula. Our case suggests that bowel rest for extended periods may be necessary for severe cases of FPIES, while endoscopy may be helpful in the differential diagnosis and the therapeutic management of these cases.

Key words: Amino acid-based formula, Cow's milk allergy, Food allergy, Food protein induced enterocolitis syndrome, Oral food challenge.

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